/aca/ - Academic Topics

Scary https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702407/

https://schaechter.asmblog.org/schaechter/2021/05/prokaryotic-organelles-yes-there-are-such-things.html a blog post on prokaryotic organelles the entire blog is pretty neat if you're interested in bio stuff

>>96 E.T. Jaynes' The logic of Science A logic -> bayesian probability -> information theory angle of statistics. Absolutely love the way it ties everything together from that standpoint, possibly start with Shannon's A Mathematical Theory of Communication for the information-theory intro to entropy if you aren't familiar with the idea. I was a bench scientist forever and it really bothered me no one could adequately explain why we use certain things, like assuming the t or normal distribution for data without much reasoning. The principal of maximum entropy provides and easy answer (assuming a finite variance, the normal distribution is the maximum entropy distribution to assume) and it just fit so nicely.

so there's this funny DOI: 10.1002/(sici)1097-4628(19981205)70:10<1939::aid-app8>3.0.co;2-g "Investigation of Alkaline Hydrolysis of polyethyelene terepthtalate by differential scanning calorimetry and thermogravimetric analysis" no idea how calorimetry works and why ppl use it but that's not what matters this paper was made by happas in the past century and can be summarized as "we tried to recycle plastics, it works" the plastic is called PET and it's basically 1,4 butanediol and terephthalic acid and 1,4 butanediol metabolizes into GHB inside of your body in a few minutes which makes GABA stuff in your brain spin right round insanely fast way better than alcohol and those red mushrooms so yeah if you don't like brewing or despise alcohol you can still easily fuck up your brain at home using plastics and toilet cleaners though hydrolysis takes a lot of time 10 grams of PET can take you like six or eight hours i recommend speeding things up by adding a bit of ethanol as a catalyst to your NaOH solution (KOH decomposes 1,4 into an unfunny glycol ) oh yeah there's also that terephtalic acid it's not "toxic" but there are lots of it you may want to remove it and most of the other nasty stuff by adding sulfuric or hydrochloric acid until the participate won't stop forming (stop as soon as it forms or you will burn your stomach) it also looks really cool you just one little drop and lots of crystals appear the participate is the nasty stuff just filter it out through a toilet paper and throw it away well it's kinda useful for other things maybe leave it 1,4 can be easily converted into GBL and then GHB but only the letters change effects are the same (and GHB is a salt while others are liquids) there was that one cool paper on dehydrogenation of 1,4 that yields GBL but i kinda lost it in my file directory labyrinth oh and yeah i just did some math 10 grams of pure PET will yield around 3/4 grams of 1,4 which is like two doses for non-tolerant people also some PETs have some brominated stuff that makes it hard to burn and that's really bad because ingestion of brominated things leads to a horrible death from cancer and it's almost impossible to filter those brominated things out so check how well your plastic burns before using it maybe i'll make a proper step by step guide later yeah i guess i will parody that asuka's meth lab webm someday too lazy rn

>PET >it's basically 1,4 butanediol and terephthalic acid oopsie woopsie i made a fucky wucky so yeah plastic that's actually a 1,4 butanediol and terephthalic acid is called PBT and you should use it instead PET will yield some 1,4 but most of it will be 1,2 and 1,3 fuck i should proof read what i write